[HTML][HTML] Ectopic fat and insulin resistance: pathophysiology and effect of diet and lifestyle interventions

M Snel, JT Jonker, J Schoones, H Lamb… - International journal of …, 2012 - hindawi.com
The storage of triglyceride (TG) droplets in nonadipose tissues is called ectopic fat storage.
Ectopic fat is associated with insulin resistance and type 2 diabetes mellitus (T2DM). Not the …

[HTML][HTML] Paleolithic nutrition for metabolic syndrome: systematic review and meta-analysis

EW Manheimer, EJ van Zuuren, Z Fedorowicz… - The American journal of …, 2015 - Elsevier
Background: Paleolithic nutrition, which has attracted substantial public attention lately
because of its putative health benefits, differs radically from dietary patterns currently …

[HTML][HTML] Effects of low-carbohydrate-compared with low-fat-diet interventions on metabolic control in people with type 2 diabetes: a systematic review including …

EJ van Zuuren, Z Fedorowicz, T Kuijpers… - The American journal of …, 2018 - Elsevier
Background It remains uncertain which diet is best for people with type 2 diabetes (T2D).
Objective We compared the effects of dietary carbohydrate restriction with fat restriction on …

Prolonged caloric restriction in obese patients with type 2 diabetes mellitus decreases myocardial triglyceride content and improves myocardial function

S Hammer, M Snel, HJ Lamb, IM Jazet… - Journal of the American …, 2008 - jacc.org
Objectives: This study sought to assess the effects of prolonged caloric restriction in obese
patients with type 2 diabetes mellitus (T2DM) on myocardial triglyceride (TG) content and …

Bromocriptine: a novel approach to the treatment of type 2 diabetes.

H Pijl, S Ohashi, M Matsuda, Y Miyazaki… - Diabetes …, 2000 - Am Diabetes Assoc
OBJECTIVE: In vertebrates, body fat stores and insulin action are controlled by the temporal
interaction of circadian neuroendocrine oscillations. Bromocriptine modulates …

[HTML][HTML] Fasting mimicking diet as an adjunct to neoadjuvant chemotherapy for breast cancer in the multicentre randomized phase 2 DIRECT trial

S de Groot, RT Lugtenberg, D Cohen… - Nature …, 2020 - nature.com
Short-term fasting protects tumor-bearing mice against the toxic effects of chemotherapy
while enhancing therapeutic efficacy. We randomized 131 patients with HER2-negative …

[HTML][HTML] The effects of short-term fasting on tolerance to (neo) adjuvant chemotherapy in HER2-negative breast cancer patients: a randomized pilot study

S de Groot, MPG Vreeswijk, MJP Welters… - BMC cancer, 2015 - Springer
Background Preclinical evidence shows that short-term fasting (STF) protects healthy cells
against side effects of chemotherapy and makes cancer cells more vulnerable to it. This pilot …

Increased stress, weight gain and less exercise in relation to glycemic control in people with type 1 and type 2 diabetes during the COVID-19 pandemic

MM Ruissen, H Regeer, CP Landstra… - BMJ Open Diabetes …, 2021 - drc.bmj.com
Introduction Lockdown measures have a profound effect on many aspects of daily life
relevant for diabetes self-management. We assessed whether lockdown measures, in the …

Hypocretin deficiency in narcoleptic humans is associated with abdominal obesity

SW Kok, S Overeem, TLS Visscher… - Obesity …, 2003 - Wiley Online Library
Objective: To determine the prevalence of obesity among patients with narcolepsy, to
estimate associated long‐term health risks on the basis of waist circumference, and to …

[HTML][HTML] Dietary fat content alters insulin-mediated glucose metabolism in healthy men

PH Bisschop, J de Metz, MT Ackermans… - The American journal of …, 2001 - Elsevier
Background: A high dietary fat intake is involved in the pathogenesis of insulin resistance.
Objective: The aim was to compare the effect of different amounts of dietary fat on hepatic …