The classification of glomerulonephritis in systemic lupus erythematosus revisited. The
currently used classification reflects our understanding of the pathogenesis of the various …

The most problematic issue in clinical nephrology is the relentless and progressive increase
in patients with ESRD (end-stage renal disease) worldwide. The impact of diabetic …

Background IgG4-related disease has attracted wide attention recently. It is characterized by
a high level of serum IgG4 and dense infiltration of IgG4-positive plasma cells into multiple …

There is a rapid global rise in obesity, and the link between obesity and diabetes remains
somewhat obscure. We identified an adipocytokine, designated as visceral adipose tissue …

Background Plasma uric acid has been associated with hypertension in a variety of
disorders, and has been shown to be predictive of hypertension. The mechanistic role of uric …

Objective To develop and validate revised classification criteria for granulomatosis with
polyangiitis (GPA). Methods Patients with vasculitis or comparator diseases were recruited …

Objective To develop and validate revised classification criteria for eosinophilic
granulomatosis with polyangiitis (EGPA). Methods Patients with vasculitis or comparator …

Objective To develop and validate classification criteria for microscopic polyangiitis (MPA).
Methods Patients with vasculitis or comparator diseases were recruited into an international …

Background We previously estimated the prevalence of chronic kidney disease (CKD)
stages 3–5 at 19.1 million based on data from the Japanese annual health check program …

Background Accurate estimation of the glomerular filtration rate (GFR) is crucial for the
detection of chronic kidney disease (CKD). In clinical practice, GFR is estimated from serum …