Graphene quantum dots with nitrogen-doped content dependence for highly efficient dual-modality photodynamic antimicrobial therapy and bioimaging

WS Kuo, HH Chen, SY Chen, CY Chang, PC Chen… - Biomaterials, 2017 - Elsevier
Reactive oxygen species is the main contributor to photodynamic therapy. The results of this
study show that a nitrogen-doped graphene quantum dot, serving as a photosensitizer, was …

[HTML][HTML] Human surfactant protein D binds spike protein and acts as an entry inhibitor of SARS-CoV-2 pseudotyped viral particles

MH Hsieh, N Beirag, V Murugaiah, YC Chou… - Frontiers in …, 2021 - frontiersin.org
Human SP-D is a potent innate immune molecule whose presence at pulmonary mucosal
surfaces allows its role in immune surveillance against pathogens. Higher levels of serum …

Two-photon photoexcited photodynamic therapy and contrast agent with antimicrobial graphene quantum dots

WS Kuo, CY Chang, HH Chen, CLL Hsu… - … applied materials & …, 2016 - ACS Publications
A graphene quantum dot (GQD) used as the photosensitizer with high two-photon
absorption in the near-infrared region, a large absolute cross section of two-photon …

Lactobacillus gasseri suppresses Th17 pro-inflammatory response and attenuates allergen-induced airway inflammation in a mouse model of allergic asthma

RL Jan, KC Yeh, MH Hsieh, YL Lin, HF Kao… - British Journal of …, 2012 - cambridge.org
Probiotics are normal inhabitants of the gastrointestinal tract of man and are widely
considered to exert a number of beneficial effects in many diseases. But the mechanism by …

Multiplexed graphene quantum dots with excitation-wavelength-independent photoluminescence, as two-photon probes, and in ultraviolet–near infrared bioimaging

WS Kuo, XC Shen, CY Chang, HF Kao, SH Lin… - ACS …, 2020 - ACS Publications
In this study, sorted nitrogen-doped graphene quantum dots were prepared and
subsequently conjugated with polymers. The synthesized materials exhibited excitation …

Propolis inhibits TGF-β1-induced epithelial–mesenchymal transition in human alveolar epithelial cells via PPARγ activation

HF Kao, PW Chang-Chien, WT Chang, TM Yeh… - International …, 2013 - Elsevier
Emerging evidence suggests that the transforming growth factor (TGF)-β1-induced epithelial–
mesenchymal transition (EMT) of alveolar epithelial cells (AEC) may contribute to airway …

[HTML][HTML] Goat milk consumption enhances innate and adaptive immunities and alleviates allergen-induced airway inflammation in offspring mice

HF Kao, YC Wang, HY Tseng, LSH Wu… - Frontiers in …, 2020 - frontiersin.org
Goat milk (GM), as compared to cow milk (CM), is easier for humans to digest. It also has
antioxidant and anti-inflammatory effects and can improve minor digestive disorders and …

Lactobacillus salivarius AP-32 and Lactobacillus reuteri GL-104 decrease glycemic levels and attenuate diabetes-mediated liver and kidney injury in db/db mice

PS Hsieh, HH Ho, SH Hsieh, YW Kuo… - BMJ Open Diabetes …, 2020 - drc.bmj.com
Objectives Patients with type 2 diabetes mellitus (T2DM) exhibit strong insulin resistance or
abnormal insulin production. Probiotics, which are beneficial live micro-organisms residing …

[HTML][HTML] Mite allergen decreases DC-SIGN expression and modulates human dendritic cell differentiation and function in allergic asthma

HJ Huang, YL Lin, CF Liu, HF Kao, JY Wang - Mucosal immunology, 2011 - Elsevier
House dust mites (HDMs) induce allergic asthma in sensitized individuals, although how
HDMs activate immature mucosal dendritic cells (DCs) to render the T helper cell type 2 …

Cytotoxicity of imidazole ionic liquids in human lung carcinoma A549 cell line

HL Chen, HF Kao, JY Wang… - Journal of the Chinese …, 2014 - Wiley Online Library
Due to the unique property of ionic liquids (ILs), they have become attractive media for
various types of chemical processes recently. ILs have become one of the hottest areas in …