Non-alcoholic fatty liver disease (NAFLD) is likely to be associated with elevated plasma
branched-chain amino acids (BCAAs) and may precede the development of type 2 diabetes …

Plasma branched-chain amino acids (BCAAs) are linked to metabolic disease, but their
relevance for prediction of type 2 diabetes development is unclear. We determined the …

Abstract Background and Aims Trimethylamine‐N‐oxide (TMAO), a gut microbiota‐liver
metabolite, has been associated with cardiometabolic disease. However, whether TMAO is …

The potential role of branched-chain amino acids (BCAAs) in the pathogenesis of
cardiometabolic diseases is increasingly recognized, but the association of BCAAs with …

Importance Higher plasma concentrations of vitamin B 12 have been associated with
mortality in elderly and hospitalized populations, including patients with chronic kidney …

Context High-density lipoproteins (HDL) may be protective against type 2 diabetes (T2D)
development, but HDL particles vary in size and function, which could lead to differential …

Background Triglyceride-rich lipoproteins particles (TRLP) and low density lipoprotein
particles (LDLP) vary in size. Their association with β-cell function is not well described. We …

Background Creatinine is the most widely used test to estimate the glomerular filtration rate
(GFR), but muscle mass as key determinant of creatinine next to renal function may …

Background In the failing heart, energy metabolism is shifted towards increased ketone body
oxidation. Nevertheless, the association of beta‐hydroxybutyrate (β‐OHB) with development …

Background Nonalcoholic fatty liver disease (NAFLD) is increasingly prevalent, paralleling
the obesity epidemic. Ketone bodies are produced in the liver, but it is currently uncertain …