Neurofilament light chain (NfL) is a novel biomarker of neurodegenerative diseases. It is
detectable in the peripheral blood, allowing low-invasive assessment of early signs of …

Ectopic fat is found in liver, muscle, and kidney and is known to accumulate as visceral fat. In
recent years, ectopic fat has also been observed in the pancreas, and it has been said that …

Background To examine the effects of liraglutide, a glucagon-like peptide-1 (GLP-1)
analogue, on visceral fat adiposity, appetite, food preference, and biomarkers of …

Aims We conducted a national survey to clarify the characteristics and clinical course of type
1 diabetes related to anti-programmed cell death-1 therapy. Methods We analyzed the …

Type 1 diabetes is a disease characterized by destruction of the β-cells in the pancreatic
islets. The inhibitory receptor programmed cell death-1 (PD-1) and its ligands, programmed …

Triglyceride deposit cardiomyovasculopathy (TGCV) is a newly identified disease that was
discovered in individuals who required cardiac transplantation in Japan in 2008. Defective …

Homeostasis model assessment of insulin resistance (HOMA-IR) is a simple and useful
method for evaluating insulin sensitivity. But it is difficult to apply to type2 diabetes patients …

Aims/hypothesis Immunomodulators blocking cytotoxic T-lymphocyte-associated protein 4
(CTLA-4) and programmed cell death protein 1 (PD-1) or programmed death-ligand 1 (PD …

The distribution and location of the virulence-factor genes of Vibrio parahaemolyticus, tdh
and trh, and the structural gene of urease, ureC, were examined on the genomic DNAs of …

Background We recently reported that short-term treatment with liraglutide (20.0±6.4 days)
reduced body weight and improved some scales of eating behavior in Japanese type 2 …