The heart is composed of several cell types including cardiomyocytes, cardiac fibroblasts,
endothelial, and smooth muscle cells. In addition to these major cell types, cardiac …

Under normal physiological conditions, cardiac fibroblasts are the primary producers of
extracellular matrix and supply a mechanical scaffold for efficacious heart contractions …

Krüppel-like factor 5 (KLF5) is a zinc-finger transcription factor known to play a pivotal role in
the pathogenesis of cardiovascular disease. Here, we show that neonatal heterozygous …

The heart contains various types of cells, including cardiomyocytes, cardiac fibroblasts,
many kinds of immune cells and vascular cells. Initial studies mainly focused on …

Renal tubulointerstitial damage is the final common pathway leading from chronic kidney
disease to end-stage renal disease. Inflammation is clearly involved in tubulointerstitial …

Ghost imaging is a technique used to produce an object's image without using a spatially
resolving detector. Here we develop a technique we term “ghost cytometry,” an image-free …

Obesity and metabolic syndrome are increasingly recognized as major risk factors for
cardiovascular disease. Herein we show that Krüppel-like transcription factor 5 (KLF5) is a …

Background: Heart failure (HF) and atrial fibrillation (AF) are growing in prevalence
worldwide. Few studies have assessed to what extent stage 1 hypertension in the 2017 …

JCS 2017 Guideline on Prevention and Treatment of Infective Endocarditis Toggle navigation
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Background—It has been proposed that bone marrow–derived cells infiltrate the neointima,
where they differentiate into smooth muscle (SM) cells; however, technical limitations have …