In Japan, original researches on nephrotic syndrome (NS) were initially performed by the
Ministry of Health, Labour and Welfare (MHLW) NS research group. The first definition of NS …

During phagocytosis, gp91 phox, the catalytic subunit of the phagocyte NADPH oxidase,
becomes activated to produce superoxide, a precursor of microbicidal oxidants. Currently …

Chronic kidney disease–mineral and bone disorder (CKD–MBD) is a systemic disorder that
affects multiple organs and systems and increases the risk of morbidity and mortality in …

Objective Lupus nephritis, which shows various histologic patterns, is a serious complication
of systemic lupus erythematosus (SLE). We previously demonstrated the importance of Th1 …

Direct involvement of the receptor-mediated apoptotic pathways in cisplatin-induced renal
tubular cell death. Background Tumor necrosis factor (TNF) receptor family members, such …

BACKGROUND: Chronic kidney disease (CKD) is associated with increased risk of coronary
heart disease. However, information regarding the histopathologic characteristics of …

Multiple disorders underlie the development of CRS. Current treatment options include renin–
angiotensin system blockade and volume control, but remain limited. A multidisciplinary …

Objective The renal resistive index (RI) and pulsatility index (PI), measured using Doppler
ultrasonography, reflect intrarenal vascular resistance. We evaluated the relationship …

Renal anemia is a complication of chronic kidney disease. Guidelines for safe and effective
treatment in patients with renal anemia are needed. The Japanese Society for Dialysis …

Hyperphosphatemia contributes to increased cardiovascular mortality through vascular
calcification (VC) in patients with chronic kidney disease (CKD). Malnutrition and …