[HTML][HTML] Advances in clinical applications of kisspeptin-GnRH pathway in female reproduction

KL Hu, Z Chen, X Li, E Cai, H Yang, Y Chen… - Reproductive Biology …, 2022 - Springer
Background Kisspeptin is the leading upstream regulator of pulsatile and surge
Gonadotrophin-Releasing Hormone secretion (GnRH) in the hypothalamus, which acts as …

[HTML][HTML] Nonalcoholic fatty liver disease: pathogenesis and treatment in traditional Chinese medicine and western medicine

T Shi, L Wu, W Ma, L Ju, M Bai, X Chen, S Liu… - Evidence-Based …, 2020 - hindawi.com
Nonalcoholic Fatty Liver Disease (NAFLD) is one of the most important causes of liver
disease worldwide and probably destined to become the leading cause of end-stage liver …

Effects of prediabetes mellitus alone or plus hypertension on subsequent occurrence of cardiovascular disease and diabetes mellitus: longitudinal study

M Qiu, W Shen, X Song, L Ju, W Tong, H Wang… - …, 2015 - Am Heart Assoc
Whether prediabetes mellitus alone or combined with other disorders means a higher risk
for cardiovascular disease (CVD) is still controversial. This study aimed to investigate the …

Liraglutide ameliorates non‐alcoholic fatty liver disease by enhancing mitochondrial architecture and promoting autophagy through the SIRT1/SIRT3–FOXO3a …

W Tong, L Ju, M Qiu, Q Xie, Y Chen… - Hepatology …, 2016 - Wiley Online Library
Aim Overwhelming oxidative stress is implicated as crucial in the pathogenesis of non‐
alcoholic fatty liver disease (NAFLD). Liraglutide, a well‐established antidiabetes drug, was …

[HTML][HTML] N-acetylcysteine protects against liver injure induced by carbon tetrachloride via activation of the Nrf2/HO-1 pathway

Z Cai, Q Lou, F Wang, E Li, J Sun, H Fang… - International journal of …, 2015 - ncbi.nlm.nih.gov
Chronic liver injury is an important clinical problem which eventually leads to cirrhosis,
hepatocellular carcinoma and end-stage liver failure. It is well known that cell damage …

[HTML][HTML] Obesity-associated inflammation triggers an autophagy–lysosomal response in adipocytes and causes degradation of perilipin 1

L Ju, J Han, X Zhang, Y Deng, H Yan, C Wang… - Cell death & …, 2019 - nature.com
In obesity, adipocytes exhibit high metabolic activity accompanied by an increase in lipid
mobilization. Recent findings indicate that autophagy plays an important role in metabolic …

Integrated water resource security evaluation of Beijing based on GRA and TOPSIS

J Dai, J Qi, J Chi, S Chen, J Yang, L Ju… - Frontiers of Earth Science …, 2010 - Springer
Security evaluation has become a hot topic in the research field of water resource
management. In this paper, we established a novel water resource security indicator system …

Gender-related affecting factors of prediabetes on its 10-year outcome

X Song, M Qiu, H Wang, W Tong, L Ju, L Gu… - BMJ Open Diabetes …, 2016 - drc.bmj.com
Objective To investigate the gender-related affecting factors of prediabetes on its 10-year
outcome, in a longitudinal study. Methods and results This longitudinal population-based …

[HTML][HTML] Enhanced expression of Survivin has distinct roles in adipocyte homeostasis

L Ju, X Zhang, Y Deng, J Han, J Yang, S Chen… - Cell Death & …, 2018 - nature.com
Although precisely controlled lipolysis is crucial for maintaining physiological levels of
circulating free fatty acids in response to energetic stress, the underlying mechanisms by …

Diagnostic value of kisspeptin levels on early pregnancy outcome: a systematic review and meta-analysis

KL Hu, Z Chen, W Deng, X Li, L Ju, H Yang… - Reproductive …, 2022 - Springer
The objective of this study is to investigate whether kisspeptin levels in early pregnancy
have a better diagnostic value on early pregnancy outcome as compared with human …