The ARIC (Atherosclerosis Risk In Communities) Study: JACC Focus Seminar 3/8

JD Wright, AR Folsom, J Coresh, AR Sharrett… - Journal of the American …, 2021 - jacc.org
Abstract ARIC (Atherosclerosis Risk In Communities) initiated community-based
surveillance in 1987 for myocardial infarction and coronary heart disease (CHD) incidence …

Misclassification rates for current smokers misclassified as nonsmokers.

AJ Wells, PB English, SF Posner… - … journal of public …, 1998 - ajph.aphapublications.org
OBJECTIVES: This paper provides misclassification rates for current cigarette smokers who
report themselves as nonsmokers. Such rates are important in determining smoker …

Association of an intensive lifestyle intervention with remission of type 2 diabetes

EW Gregg, H Chen, LE Wagenknecht, JM Clark… - Jama, 2012 - jamanetwork.com
Context The frequency of remission of type 2 diabetes achievable with lifestyle intervention
is unclear. Objective To examine the association of a long-term intensive weight-loss …

Cigarette smoking and progression of atherosclerosis: The Atherosclerosis Risk in Communities (ARIC) Study

G Howard, LE Wagenknecht, GL Burke, A Diez-Roux… - Jama, 1998 - jamanetwork.com
Context.—Cigarette smoking is a powerful risk factor for incident heart disease and stroke,
but the relationship of active and passive smoking with the progression of atherosclerosis …

Association between midlife vascular risk factors and estimated brain amyloid deposition

RF Gottesman, ALC Schneider, Y Zhou, J Coresh… - Jama, 2017 - jamanetwork.com
Importance Midlife vascular risk factors have been associated with late-life dementia.
Whether these risk factors directly contribute to brain amyloid deposition is less well …

Liver markers and development of the metabolic syndrome: the insulin resistance atherosclerosis study

AJG Hanley, K Williams, A Festa, LE Wagenknecht… - Diabetes, 2005 - Am Diabetes Assoc
Nonalcoholic fatty liver disease (NAFLD) is emerging as a component of the metabolic
syndrome, although it is not known whether markers of NAFLD, including elevated …

Diabetes in midlife and cognitive change over 20 years: a cohort study

AM Rawlings, AR Sharrett, ALC Schneider… - Annals of internal …, 2014 - acpjournals.org
Background: Type 2 diabetes is associated with dementia risk, but evidence is limited for
possible associations of diabetes and prediabetes with cognitive decline. Objective: To …

Genome-wide association meta-analysis identifies 17 loci associated with nonalcoholic fatty liver disease

Y Chen, X Du, A Kuppa, MF Feitosa, LF Bielak… - Nature Genetics, 2023 - nature.com
Nonalcoholic fatty liver disease (NAFLD) is common and partially heritable and has no
effective treatments. We carried out a genome-wide association study (GWAS) meta …

Microalbuminuria is associated with insulin resistance in nondiabetic subjects: the insulin resistance atherosclerosis study.

L Mykkänen, DJ Zaccaro, LE Wagenknecht… - Diabetes, 1998 - Am Diabetes Assoc
Microalbuminuria is associated with excess cardiovascular mortality in both diabetic and
nondiabetic subjects. Patients with NIDDM and microalbuminuria are more insulin resistant …

Effect of a 12-month intensive lifestyle intervention on hepatic steatosis in adults with type 2 diabetes

M Lazo, SF Solga, A Horska, S Bonekamp… - Diabetes …, 2010 - Am Diabetes Assoc
OBJECTIVE Weight loss through lifestyle changes is recommended for nonalcoholic fatty
liver disease (NAFLD). However, its efficacy in patients with type 2 diabetes is unproven …