Several species of intestinal bacteria have been associated with enhanced efficacy of
checkpoint blockade immunotherapy, but the underlying mechanisms by which the …

The incidence of differentiated thyroid cancer has been increasing in the last decades all
over the world. Such a steady growth cannot be entirely attributable to more intensive thyroid …

Aim To conduct a meta‐analysis of randomized clinical trials (RCTs) to investigate whether
there is an association between glucagon‐like peptide‐1 receptor agonist (GLP‐1RA) …

Human glioblastomas harbour a subpopulation of glioblastoma stem cells that drive
tumorigenesis. However, the origin of intratumoural functional heterogeneity between …

Functional heterogeneity within tumors presents a significant therapeutic challenge. Here
we show that quiescent, therapy-resistant Sox2+ cells propagate sonic hedgehog subgroup …

BACKGROUND The follow‐up of patients with differentiated thyroid carcinoma (DTC) is
traditionally carried out with 131I whole body scan (131I WBS) and serum thyroglobulin (Tg) …

Diabetes and cancer are common, chronic, and potentially fatal diseases that frequently co-
exist. Observational studies have reported an increased risk of cancer in patients with …

Embryonal tumors with multilayered rosettes (ETMRs) are rare, deadly pediatric brain
tumors characterized by high-level amplification of the microRNA cluster C19MC,. We …

Replicative immortality is a hallmark of cancer cells governed by telomere maintenance.
Approximately 90% of human cancers maintain their telomeres by activating telomerase …

Mutations in the histone 3 variant H3. 3 have been identified in one-third of pediatric
glioblastomas (GBMs), but not in adult tumors. Here we show that H3. 3 is a dynamic …