Stress and diabetes mellitus

RS Surwit, MS Schneider, MN Feinglos - Diabetes care, 1992 - Am Diabetes Assoc
Stress is a potential contributor to chronic hyperglycemia in diabetes. Stress has long been
shown to have major effects on metabolic activity. Energy mobilization is a primary result of …

[HTML][HTML] Oral agents in the management of type 2 diabetes mellitus

B Luna, MN Feinglos - American family physician, 2001 - aafp.org
Despite exhaustive efforts to better manage patients with type 2 diabetes mellitus (formerly
known as non-insulin-dependent diabetes mellitus), attempts at maintaining near normal …

Diet-induced type II diabetes in C57BL/6J mice

RS Surwit, CM Kuhn, C Cochrane, JA McCubbin… - Diabetes, 1988 - Am Diabetes Assoc
We investigated the effects of diet-induced obesity on glucose metabolism in two strains of
mice, C57BL/6J and A/J. Twenty animals from each strain received ad libitum exposure to a …

Effect of initial combination therapy with sitagliptin, a dipeptidyl peptidase-4 inhibitor, and metformin on glycemic control in patients with type 2 diabetes

BJ Goldstein, MN Feinglos, JK Lunceford… - Diabetes …, 2007 - Am Diabetes Assoc
OBJECTIVE—To assess the efficacy and safety of initial combination therapy with sitagliptin
and metformin in patients with type 2 diabetes and inadequate glycemic control on diet and …

Stress management improves long-term glycemic control in type 2 diabetes

RS Surwit, MAL Van Tilburg, N Zucker… - Diabetes …, 2002 - Am Diabetes Assoc
OBJECTIVE—There is conflicting evidence regarding the utility of stress management
training in the treatment of diabetes. The few studies that have shown a therapeutic effect of …

The effects of baseline characteristics, glycaemia treatment approach, and glycated haemoglobin concentration on the risk of severe hypoglycaemia: post hoc …

ME Miller, DE Bonds, HC Gerstein, ER Seaquist… - Bmj, 2010 - bmj.com
Objectives To investigate potential determinants of severe hypoglycaemia, including
baseline characteristics, in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) …

Exercise and weight loss reduce blood pressure in men and women with mild hypertension: effects on cardiovascular, metabolic, and hemodynamic functioning

JA Blumenthal, A Sherwood… - Archives of internal …, 2000 - jamanetwork.com
Background Lifestyle modifications have been recommended as the initial treatment strategy
for lowering high blood pressure (BP). However, evidence for the efficacy of exercise and …

Once-weekly albiglutide versus once-daily liraglutide in patients with type 2 diabetes inadequately controlled on oral drugs (HARMONY 7): a randomised, open-label …

RE Pratley, MA Nauck, AH Barnett… - The lancet Diabetes & …, 2014 - thelancet.com
Background As new members of a drug class are developed, head-to-head trials are an
important strategy to guide personalised treatment decisions. We assessed two glucagon …

Reversal of diet-induced obesity and diabetes in C57BL/6J mice

PI Parekh, AE Petro, JM Tiller, MN Feinglos, RS Surwit - Metabolism, 1998 - Elsevier
We have previously shown that C57BL/6J (B6) mice develop severe obesity and diabetes if
weaned onto high-fat diets, whereas A/J mice tend to be obesity and diabetes-resistant. The …

HARMONY 3: 104-week randomized, double-blind, placebo-and active-controlled trial assessing the efficacy and safety of albiglutide compared with placebo …

B Ahrén, SL Johnson, M Stewart, DT Cirkel… - Diabetes …, 2014 - Am Diabetes Assoc
OBJECTIVE To compare the efficacy and safety of weekly albiglutide with daily sitagliptin,
daily glimepiride, and placebo. Research Design And Methods Patients with type 2 diabetes …