The Japanese Society of Hypertension guidelines for the management of hypertension (JSH 2019)

S Umemura, H Arima, S Arima, K Asayama… - Hypertension …, 2019 - nature.com
The Japanese Society of Hypertension (JSH) revised the Guidelines for the Management of
Hypertension 2014 (JSH 2014), and published the JSH 2019. In the development of the JSH …

Myosin phosphatase: structure, regulation and function

M Ito, T Nakano, F Erdődi, DJ Hartshorne - Molecular and cellular …, 2004 - Springer
Phosphorylation of myosin II plays an important role in many cell functions, including smooth
muscle contraction. The level of myosin II phosphorylation is determined by activities of …

Myosin light chain phosphatase: subunit composition, interactions and regulation

DJ Hartshorne, M Ito, F Erdo¨ di - Journal of Muscle Research & Cell …, 1998 - Springer
Background Phosphorylation of proteins is a major factor in regulation of many cell
processes. Most of the kinases phosphorylate either Ser/Thr or Tyr and associated with each …

Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)

K Kimura, M Ito, M Amano, K Chihara, Y Fukata… - Science, 1996 - science.org
The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC)
phosphorylation, which results in contraction of smooth muscle and interaction of actin and …

[HTML][HTML] Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase)

M Amano, M Ito, K Kimura, Y Fukata, K Chihara… - Journal of Biological …, 1996 - ASBMB
The small GTPase Rho is implicated in physiological functions associated with actin-myosin
filaments such as cytokinesis, cell motility, and smooth muscle contraction. We have recently …

Rho‐associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho.

T Matsui, M Amano, T Yamamoto, K Chihara… - The EMBO …, 1996 - embopress.org
The small GTP binding protein Rho is implicated in cytoskeletal responses to extracellular
signals such as lysophosphatidic acid to form stress fibers and focal contacts. Here we have …

The Japanese Society of Hypertension guidelines for the management of hypertension (JSH 2014)

K Shimamoto, K Ando, T Fujita… - Hypertension …, 2014 - keio.elsevierpure.com
The Japanese Society of Hypertension guidelines for the management of hypertension (JSH
2014) — Keio University Skip to main navigation Skip to search Skip to main content Keio …

Phosphorylation of myosin-binding subunit (MBS) of myosin phosphatase by Rho-kinase in vivo

Y Kawano, Y Fukata, N Oshiro, M Amano… - The Journal of cell …, 1999 - rupress.org
Rho-associated kinase (Rho-kinase), which is activated by the small GTPase Rho,
phosphorylates myosin-binding subunit (MBS) of myosin phosphatase and thereby …

[HTML][HTML] Rho-associated kinase directly induces smooth muscle contraction through myosin light chain phosphorylation

Y Kureishi, S Kobayashi, M Amano, K Kimura… - Journal of Biological …, 1997 - ASBMB
Small GTPase Rho plays pivotal roles in the Ca 2+ sensitization of smooth muscle.
However, the GTP-bound active form of Rho failed to exert Ca 2+-sensitizing effects in …

Regulation of myosin phosphatase by a specific interaction with cGMP-dependent protein kinase Iα

HK Surks, N Mochizuki, Y Kasai, SP Georgescu… - Science, 1999 - science.org
Contraction and relaxation of smooth muscle are regulated by myosin light-chain kinase and
myosin phosphatase through phosphorylation and dephosphorylation of myosin light …