Pharmacological challenges to oncogenic Ras-expressing cancer cells have shown a novel
type of cell death, ferroptosis, which requires intracellular iron. In the present study, we …

Background Terminal restriction fragment length polymorphism (T-RFLP) analysis is a
powerful tool to assess the diversity of a microbial community. In this study, we performed T …

Background: We investigated the effects of pectin, a soluble dietary fiber, on the
morphological parameters of the small intestine. In addition, we tested the effects of butyrate …

Aim: Although pectin, a dietary fibre, has been suggested to possess some trophic effects on
the intestine, the mechanisms involved remain unclear. This study aimed to evaluate the …

The relationship between skeletal muscle volume and the prognosis of patients with
inflammatory bowel disease (IBD) remains undetermined. We conducted a retrospective …

Background Multidrug resistance protein 4 (MRP4) functions as an efflux pump of
nucleoside monophosphate analogs, such as 6-mercaptopurine (6-MP) and 6-thioguanine …

Background and aims Few data are available to support the clinical relevance of infliximab
(IFX) trough levels for prediction of endoscopic disease activity in Crohn's disease (CD). This …

Background/aim The appearance of anti-adalimumab antibodies (AAAs) is associated with
low serum adalimumab (ADA) trough levels and a decrease of clinical response. The goal of …

Objectives Although an elemental diet has been established as the primary treatment for
patients with Crohn's disease, the influence of dietary fat on the elemental diet remains …

Butyrate enemas have been reported to be effective in ulcerative colitis. However, long-term
use is difficult because of the troublesome procedure and the unpleasant smell. We …