In evolutionary terms, GH and intracellular STAT 5 signaling is a very old regulatory system.
Whereas insulin dominates periprandially, GH may be viewed as the primary anabolic …

With the current access to the whole genomes of various organisms and the completion of
the first draft of the human genome, there is a strong need for a structure-function …

Lipolysis is the process by which triglycerides (TGs) are hydrolyzed to free fatty acids (FFAs)
and glycerol. In adipocytes, this is achieved by sequential action of adipose TG lipase …

Examination of f/kl receptor tyrosine kinase mRNA expression by in situ hybridization
analysis revealed specific association with endothelial cells at all stages of mouse …

Obesity, diabetes, hypertension, and hyperlipidemia constitute risk factors for morbidity and
premature mortality. Based on animal and in vitro studies, resveratrol reverts these risk …

Sons of alcoholic parentage, adopted in infancy, were compared with their brothers who
were raised by the alcoholic parent. Both the adopted and nonadopted sons had high rates …

Background Levels of physical activity and variation in physical activity and sedentary time
by place and person in European children and adolescents are largely unknown. The …

Background: Myocardial utilization of 3-hydroxybutyrate (3-OHB) is increased in patients
with heart failure and reduced ejection fraction (HFrEF). However, the cardiovascular effects …

In animal models, the incretin hormone GLP-1 affects Alzheimer's disease (AD). We
hypothesized that treatment with GLP-1 or an analogue of GLP-1 would prevent …

Background Animal studies suggest a positive role for nicotinamide riboside (NR) on insulin
sensitivity and hepatic steatosis in models of obesity and type 2 diabetes. NR, an NAD+ …