Evidence-informed clinical practice recommendations for treatment of type 1 diabetes complicated by problematic hypoglycemia

P Choudhary, MR Rickels, PA Senior… - Diabetes …, 2015 - Am Diabetes Assoc
Problematic hypoglycemia, defined as two or more episodes per year of severe
hypoglycemia or as one episode associated with impaired awareness of hypoglycemia …

[HTML][HTML] Communicating the impact of communication for development: Recent trends in empirical research

N Inagaki - 2007 - books.google.com
This paper is a peer review of journals addressing the issue of the impact of development
communication in a number of development projects and programs. It provides an overview …

Renal sodium glucose cotransporter 2 inhibitors as a novel therapeutic approach to treatment of type 2 diabetes: clinical data and mechanism of action

Y Fujita, N Inagaki - Journal of diabetes investigation, 2014 - Wiley Online Library
Type 2 diabetes is characterized by impaired insulin secretion from pancreatic β‐cells
and/or reduced response of target tissues to insulin. Good glycemic control delays the …

Reconstitution of IKATP: An Inward Rectifier Subunit Plus the Sulfonylurea Receptor

N Inagaki, T Gonoi, JP Clement IV, N Namba… - Science, 1995 - science.org
A member of the inwardly rectifying potassium channel family was cloned here. The
channel, called BIR (Kir6. 2), was expressed in large amounts in rat pancreatic islets and …

[HTML][HTML] Report of the Committee on the classification and diagnostic criteria of diabetes mellitus: The Committee of the Japan Diabetes Society on the diagnostic …

Y Seino, K Nanjo, N Tajima, T Kadowaki, A Kashiwagi… - 2010 - Springer
Diabetes mellitus is a group of diseases associated with various metabolic disorders, the
main feature of which is chronic hyperglycemia due to insufficient insulin action. Its …

[HTML][HTML] A family of sulfonylurea receptors determines the pharmacological properties of ATP-sensitive K+ channels

N Inagaki, T Gonoi, JPC Iv, CZ Wang, L Aguilar-Bryan… - Neuron, 1996 - cell.com
We have cloned an isoform of the sulfonylurea receptor (SUR), designated SUR2.
Coexpression of SUR2 and the inward rectifier K+ channel subunit Kir6. 2 in COS1 cells …

Over-expression of facilitative glucose transporter genes in human cancer

T Yamamoto, Y Seino, H Fukumoto, G Koh… - Biochemical and …, 1990 - Elsevier
The expression of five facilitative glucose transporter genes, GLUT1 (erythrocyte type),
GLUT2 (liver type), GLUT3 (brain type), GLUT4 (muscle/fat type), and GLUT5 (small intestine …

Proposal for new diagnostic criteria for low skeletal muscle mass based on computed tomography imaging in Asian adults

Y Hamaguchi, T Kaido, S Okumura, A Kobayashi… - Nutrition, 2016 - Elsevier
Objectives Low skeletal muscle, referred to as sarcopenia, has been shown to be an
independent predictor of lower overall survival in various kinds of diseases. Several studies …

[HTML][HTML] Cloning and Functional Characterization of a Novel ATP-sensitive Potassium Channel Ubiquitously Expressed in Rat Tissues, including Pancreatic Islets …

N Inagaki, Y Tsuura, N Namba, K Masuda… - Journal of Biological …, 1995 - ASBMB
ATP-sensitive K+(K ATP) channels play a crucial role in coupling metabolic energy to the
membrane potential of cells. We have isolated a cDNA encoding a novel member (uK ATP …

Protective role of ATP-sensitive potassium channels in hypoxia-induced generalized seizure

K Yamada, JJ Ji, H Yuan, T Miki, S Sato, N Horimoto… - Science, 2001 - science.org
Adenosine triphosphate (ATP)–sensitive potassium (KATP) channels are activated by
various metabolic stresses, including hypoxia. The substantia nigra pars reticulata (SNr), the …