User profiles for "author:Olga Gornik"
 | Olga GornikUniversity of Zagreb Faculty of Pharmacy and Biochemistry Verified email at pharma.unizg.hr Cited by 6403 |
Glycosylation of serum proteins in inflammatory diseases
Inflammatory diseases are accompanied by numerous changes at the site of inflammation
as well as many systemic physiological and biochemical changes. In the past two decades …
as well as many systemic physiological and biochemical changes. In the past two decades …
Alternative glycosylation modulates function of IgG and other proteins—implications on evolution and disease
BACKGROUND: Nearly all membrane and secreted proteins, as well as numerous
intracellular proteins are glycosylated. However, contrary to proteins which are defined by …
intracellular proteins are glycosylated. However, contrary to proteins which are defined by …
Altered N‐glycosylation profiles as potential biomarkers and drug targets in diabetes
N‐glycosylation is a ubiquitous protein modification, and N‐glycosylation profiles are
emerging as both biomarkers and functional effectors in various types of diabetes. Genome …
emerging as both biomarkers and functional effectors in various types of diabetes. Genome …
[HTML][HTML] High throughput isolation and glycosylation analysis of IgG–variability and heritability of the IgG glycome in three isolated human populations
M Pučić, A Knežević, J Vidič, B Adamczyk… - Molecular & Cellular …, 2011 - ASBMB
All immunoglobulin G molecules carry N-glycans, which modulate their biological activity.
Changes in N-glycosylation of IgG associate with various diseases and affect the activity of …
Changes in N-glycosylation of IgG associate with various diseases and affect the activity of …
[HTML][HTML] Loci Associated with N-Glycosylation of Human Immunoglobulin G Show Pleiotropy with Autoimmune Diseases and Haematological Cancers
Glycosylation of immunoglobulin G (IgG) influences IgG effector function by modulating
binding to Fc receptors. To identify genetic loci associated with IgG glycosylation, we …
binding to Fc receptors. To identify genetic loci associated with IgG glycosylation, we …
Glycans are a novel biomarker of chronological and biological ages
Fine structural details of glycans attached to the conserved N-glycosylation site significantly
not only affect function of individual immunoglobulin G (IgG) molecules but also mediate …
not only affect function of individual immunoglobulin G (IgG) molecules but also mediate …
[HTML][HTML] Genomics meets glycomics—the first GWAS study of human N-glycome identifies HNF1α as a master regulator of plasma protein fucosylation
G Lauc, A Essafi, JE Huffman, C Hayward… - PLoS …, 2010 - journals.plos.org
Over half of all proteins are glycosylated, and alterations in glycosylation have been
observed in numerous physiological and pathological processes. Attached glycans …
observed in numerous physiological and pathological processes. Attached glycans …
Effects of aging, body mass index, plasma lipid profiles, and smoking on human plasma N-glycans
Protein glycosylation affects nearly all molecular interactions at the cell surface and in the
intercellular space. Many of the physiological variations which are part of homeostatic …
intercellular space. Many of the physiological variations which are part of homeostatic …
Variability, heritability and environmental determinants of human plasma N-glycome
Plasma glycans were analyzed in 1008 individuals to evaluate variability and heritability, as
well as the main environmental determinants that affect glycan structures. By combining …
well as the main environmental determinants that affect glycan structures. By combining …
[PDF][PDF] Association of systemic lupus erythematosus with decreased immunosuppressive potential of the IgG glycome
Objective Glycans attached to the Fc portion of IgG are important modulators of IgG effector
functions. Interindividual differences in IgG glycome composition are large and they …
functions. Interindividual differences in IgG glycome composition are large and they …