Prevalence of and reasons for discontinuation of continuous subcutaneous insulin infusion in people with type 1 diabetes: a systematic review

P Dekker, HJ Aanstoot, T Sas, M De Vries… - Diabetes technology …, 2023 - liebertpub.com
The introduction of continuous subcutaneous insulin infusion in clinical care has led to more
optimal glycemic and quality-of-life outcomes, compared with multiple daily injections (MDI) …

Rapid flow cytometric method for measuring senescence associated β‐galactosidase activity in human fibroblasts

G Noppe, P Dekker… - Cytometry Part A …, 2009 - Wiley Online Library
Senescence associated‐β‐galactosidase (SA‐β‐gal) activity is a widely used marker for
cellular senenescence. SA‐β‐gal activity is routinely detected cytochemically, manually …

When elasticity affects drop coalescence

PJ Dekker, MA Hack, W Tewes, C Datt, A Bouillant… - Physical review …, 2022 - APS
The breakup and coalescence of drops are elementary topological transitions in interfacial
flows. The breakup of a drop changes dramatically when polymers are added to the fluid …

Rapid viscoelastic spreading

A Bouillant, PJ Dekker, MA Hack, JH Snoeijer - Physical Review Fluids, 2022 - APS
We investigate the rapid spreading dynamics of a viscoelastic drop on a solid. Upon contact,
surface tension drives a fast motion of the contact line along the substrate. Here we resolve …

Stress‐induced responses of human skin fibroblasts in vitro reflect human longevity

P Dekker, AB Maier, D Van Heemst… - Aging …, 2009 - Wiley Online Library
Unlike various model organisms, cellular responses to stress have not been related to
human longevity. We investigated cellular responses to stress in skin fibroblasts that were …

Residual C-peptide secretion and hypoglycemia awareness in people with type 1 diabetes

MJ Wellens, CE Vollenbrock, P Dekker… - BMJ Open Diabetes …, 2021 - drc.bmj.com
Introduction This study aimed to assess the association between fasting serum C-peptide
levels and the presence of impaired awareness of hypoglycemia (IAH) in people with type 1 …

How low is really low? Comparison of two C‐peptide assays to establish residual C‐peptide production in type 1 diabetes

K de Leur, C Vollenbrock, P Dekker… - Diabetic …, 2022 - Wiley Online Library
Introduction C‐peptide is an important marker to assess residual insulin production in
individuals with type 1 diabetes (T1D). The accuracy and detection limits of C‐peptide …

[HTML][HTML] Effects of peri-conception and pregnancy glycemic variability on pregnancy and perinatal complications in type 1 diabetes: A pilot study

R Hoek-Hogchem, SA Bovenberg… - Experimental and …, 2022 - thieme-connect.com
Background Not much is known about the effects of glycemic variability (GV) during the pre-
and periconception period on pregnancy/perinatal complications. GV could potentially …

Microarray-based identification of age-dependent differences in gene expression of human dermal fibroblasts

P Dekker, D Gunn, T McBryan, RW Dirks… - Mechanisms of ageing …, 2012 - Elsevier
Senescence is thought to play an important role in the progressive age-related decline in
tissue integrity and concomitant diseases, but not much is known about the complex …

Protection by Food‐derived Antioxidants from UV‐A1‐Induced Photodamage, Measured Using Living Skin Equivalents

P Dekker, WE Parish, MR Green - Photochemistry and …, 2005 - Wiley Online Library
In a study of biomarkers of ultraviolet‐A1 radiation (UV‐A1)‐induced skin damage, living
skin equivalent cultures (LSE) were treated with the antioxidants hesperetin and quercetin‐3 …