BACKGROUND: Optimizing liposomal vehicles for targeted delivery to the brain has
important implications for the treatment of brain tumors. The promise of efficient, brain …

Effects of radiofrequency ablation (RFA) treatment of atrial fibrillation can be limited by the
ability to characterize the tissue in contact. Parameters obtained by conventional catheters …

Nanoparticles such as liposomes may be used as drug delivery vehicles for brain tumor
therapy. Particle geometry and electrostatic properties have been hypothesized to be …

We present an application of spatial frequency-domain imaging (SFDI) to the wide-field
imaging of drug delivery to brain tissue. Measurements were compared with values obtained …

Transient cerebral hypoperfusion (TCH) has empirically been used to assist intraarterial (IA)
drug delivery to brain tumors. Transient (< 3 min) reduction of cerebral blood flow (CBF) …

Organoids are becoming widespread in drug-screening technologies but have been used
sparingly for cell therapy as current approaches for producing self-organized cell clusters …

Despite considerable advances in guidance of radiofrequency ablation (RFA) therapy for the
treatment of cardiac arrhythmias, success rates have been hampered by a lack of tools for …

Atrial fibrillation (Afib) can lead to life threatening conditions such as heart failure and stroke.
During Afib treatment, clinicians aim to repress unusual electrical activity by electrically …

Epicardial ablation is necessary for the treatment of ventricular tachycardias refractory to
endocardial ablation due to arrhythmic substrates involving the epicardium. The human …

Introduction The use of non-invasive vascular and perfusion diagnostics are an important
part of assessing lower extremity ulceration and amputation risk in patients with diabetes …