Effect of liraglutide, a glucagon‐like peptide‐1 analogue, on left ventricular function in stable chronic heart failure patients with and without diabetes (LIVE)—a …

A Jorsal, C Kistorp, P Holmager… - European journal of …, 2017 - Wiley Online Library
Aims To determine the effect of the glucagon‐like peptide‐1 analogue liraglutide on left
ventricular function in chronic heart failure patients with and without type 2 diabetes …

Cardiovascular effects of treatment with the ketone body 3-hydroxybutyrate in chronic heart failure patients

R Nielsen, N Møller, LC Gormsen, LP Tolbod… - Circulation, 2019 - Am Heart Assoc
Background: Myocardial utilization of 3-hydroxybutyrate (3-OHB) is increased in patients
with heart failure and reduced ejection fraction (HFrEF). However, the cardiovascular effects …

Ketone body infusion with 3‐hydroxybutyrate reduces myocardial glucose uptake and increases blood flow in humans: a positron emission tomography study

LC Gormsen, M Svart, HH Thomsen… - Journal of the …, 2017 - Am Heart Assoc
Background High levels of ketone bodies are associated with improved survival as observed
with regular exercise, caloric restriction, and—most recently—treatment with sodium …

Randomized trial of metoprolol in patients with obstructive hypertrophic cardiomyopathy

AM Dybro, TB Rasmussen, RR Nielsen… - Journal of the American …, 2021 - jacc.org
Background The use of β-adrenergic receptor blocking agents in symptomatic patients with
obstructive hypertrophic cardiomyopathy (HCM) rests on clinical experience and …

Cardiovascular and metabolic effects of 48-h glucagon-like peptide-1 infusion in compensated chronic patients with heart failure

M Halbirk, H Nørrelund, N Møller… - American Journal …, 2010 - journals.physiology.org
The incretin hormone glucagon-like peptide-1 (GLP-1) and its analogs are currently
emerging as antidiabetic medications. GLP-1 improves left ventricular ejection fraction …

[HTML][HTML] An update on targeted gene repair in mammalian cells: methods and mechanisms

NM Jensen, T Dalsgaard, M Jakobsen… - Journal of biomedical …, 2011 - Springer
Transfer of full-length genes including regulatory elements has been the preferred gene
therapy strategy for clinical applications. However, with significant drawbacks emerging …

Effects of metoprolol on exercise hemodynamics in patients with obstructive hypertrophic cardiomyopathy

AM Dybro, TB Rasmussen, RR Nielsen… - Journal of the American …, 2022 - jacc.org
Background The relationship between exercise hemodynamics, loading conditions, and
medical treatment in patients with obstructive hypertrophic cardiomyopathy (HCM) is …

[HTML][HTML] Myocardial strain assessed by feature tracking cardiac magnetic resonance in patients with a variety of cardiovascular diseases–A comparison with …

K Pryds, AH Larsen, MS Hansen, AYK Grøndal… - Scientific reports, 2019 - nature.com
Myocardial deformation assessed by speckle tracking echocardiography (STE) is
increasingly used for diagnosis, monitoring and prognosis in patients with clinical and pre …

[HTML][HTML] Ketone body 3-hydroxybutyrate elevates cardiac output through peripheral vasorelaxation and enhanced cardiac contractility

C Homilius, JM Seefeldt, JS Axelsen… - Basic Research in …, 2023 - Springer
Abstract The ketone body 3-hydroxybutyrate (3-OHB) increases cardiac output and
myocardial perfusion without affecting blood pressure in humans, but the cardiovascular …

Effect of long-term remote ischemic conditioning in patients with chronic ischemic heart failure

K Pryds, RR Nielsen, A Jorsal, MS Hansen… - Basic Research in …, 2017 - Springer
Remote ischemic conditioning (RIC) protects against acute ischemia–reperfusion injury and
may also have beneficial effects in patients with stable cardiovascular disease. We …