Diabetic retinopathy in the aging population: a perspective of pathogenesis and treatment

SP Leley, TA Ciulla… - Clinical Interventions in …, 2021 - Taylor & Francis
The elderly population in the United States is projected to almost double by the year 2050. In
addition, the numbers of diabetics are rising, along with its most common complication …

[HTML][HTML] Hematopoietic stem/progenitor involvement in retinal microvascular repair during diabetes: Implications for bone marrow rejuvenation

AD Bhatwadekar, Y Duan, M Korah, JS Thinschmidt… - Vision research, 2017 - Elsevier
The widespread nature of diabetes affects all organ systems of an individual including the
bone marrow. Long-term damage to the cellular and extracellular components of the bone …

Dapagliflozin protects neural and vascular dysfunction of the retina in diabetes

Q Luo, SP Leley, E Bello, H Dhami, D Mathew… - BMJ Open Diabetes …, 2022 - drc.bmj.com
Introduction Dapagliflozin, a sodium-glucose transporter inhibitor, effectively reduces blood
glucose and is indicated for individuals with kidney diseases and cardiovascular disorders …

588-P: diabetes leads to sodium-glucose cotransporter 2 (SGLT2) increase in the retina

SP Leley, Q Luo, AD BHATWADEKAR - Diabetes, 2019 - Am Diabetes Assoc
Methods: The retinal sections of diabetic (db/db; an animal model of type 2 diabetes) and
control (db/m) mice were analyzed for SGLT2 expression using confocal microscopy. In …