Chronic hepatitis D and hepatocellular carcinoma: a systematic review and meta-analysis of observational studies

D Alfaiate, S Clément, D Gomes, N Goossens… - Journal of …, 2020 - Elsevier
Background & Aims Chronic hepatitis D (CHD) is the most severe form of chronic viral
hepatitis but its role in the development of hepatocellular carcinoma (HCC) remains …

[HTML][HTML] A review on hepatitis D: From virology to new therapies

N Mentha, S Clément, F Negro, D Alfaiate - Journal of advanced research, 2019 - Elsevier
Hepatitis delta virus (HDV) is a defective virus that requires the hepatitis B virus (HBV) to
complete its life cycle in human hepatocytes. HDV virions contain an envelope incorporating …

3.3-million-year-old stone tools from Lomekwi 3, West Turkana, Kenya

S Harmand, JE Lewis, CS Feibel, CJ Lepre, S Prat… - Nature, 2015 - nature.com
Human evolutionary scholars have long supposed that the earliest stone tools were made
by the genus Homo and that this technological development was directly linked to climate …

α-Tocopherol specifically inactivates cellular protein kinase C α by changing its phosphorylation state

R RICCIARELLI, A TASINATO, S CLÉMENT… - Biochemical …, 1998 - portlandpress.com
The mechanism of protein kinase C (PKC) regulation by α-tocopherol has been investigated
in smooth-muscle cells. Treatment of rat aortic A7r5 smooth-muscle cells with α-tocopherol …

[HTML][HTML] Current level of evidence on causal association between hepatitis C virus and type 2 diabetes: a review

G Gastaldi, N Goossens, S Clément, F Negro - Journal of advanced …, 2017 - Elsevier
The association between hepatitis C virus (HCV) infection and type 2 diabetes (T2D) has
been known for over 20 years. Cross-sectional and longitudinal studies have shown a …

β-and γ-cytoplasmic actins display distinct distribution and functional diversity

V Dugina, I Zwaenepoel, G Gabbiani… - Journal of cell …, 2009 - journals.biologists.com
Using newly generated monoclonal antibodies, we have compared the distribution of β-and
γ-cytoplasmic actin in fibroblastic and epithelial cells, in which they play crucial roles during …

[PDF][PDF] The hepatitis C virus core protein of genotypes 3a and 1b downregulates insulin receptor substrate 1 through genotype‐specific mechanisms

V Pazienza, S Clément, P Pugnale, S Conzelman… - …, 2007 - Wiley Online Library
Both molecular and clinical evidence support a link between HCV infection and insulin
resistance. We examined the in vitro interaction between the HCV core protein of genotypes …

[HTML][HTML] Fibrogenic potential of human multipotent mesenchymal stromal cells in injured liver

RM Baertschiger, V Serre-Beinier, P Morel, D Bosco… - PloS one, 2009 - journals.plos.org
Multipotent mesenchymal stromal cells (MSC) are currently investigated clinically as cellular
therapy for a variety of diseases. Differentiation of MSC toward endodermal lineages …

α‐Actin isoform distribution in normal and failing human heart: a morphological, morphometric, and biochemical study

AJH Suurmeijer, S Clément… - The Journal of …, 2003 - Wiley Online Library
We investigated the distribution of α‐skeletal, α‐cardiac, and α‐smooth muscle actin
isoforms in human heart during development, hypertrophy, and failure. At 20 weeks of fetal …

Expression and function of α-smooth muscle actin during embryonic-stem-cell-derived cardiomyocyte differentiation

S Clément, M Stouffs, E Bettiol, S Kampf… - Journal of cell …, 2007 - journals.biologists.com
Three α-muscle actin isoforms are sequentially expressed during in vivo cardiac
development. α-Smooth muscle actin is first and transiently expressed, followed by α …