[HTML][HTML] Molecular mechanisms linking oxidative stress and diabetes mellitus

H Yaribeygi, T Sathyapalan, SL Atkin… - Oxidative medicine and …, 2020 - hindawi.com
Type 2 diabetes mellitus (T2DM) is the most prevalent metabolic disorder characterized by
chronic hyperglycemia and an inadequate response to circulatory insulin by peripheral …

[HTML][HTML] Role of the NLRP3 inflammasome in cancer

M Moossavi, N Parsamanesh, A Bahrami, SL Atkin… - Molecular cancer, 2018 - Springer
Inflammasomes are large intracellular multi-protein signalling complexes that are formed in
the cytosolic compartment as an inflammatory immune response to endogenous danger …

Monocyte‐to‐HDL‐cholesterol ratio as a prognostic marker in cardiovascular diseases

S Ganjali, AM Gotto Jr, M Ruscica… - Journal of cellular …, 2018 - Wiley Online Library
Inflammation and lipid accumulation are two basic hallmarks of atherosclerosis as a chronic
disease. Inflammation not only is a local response but can also be considered as a systemic …

A1C variability and the risk of microvascular complications in type 1 diabetes: data from the Diabetes Control and Complications Trial

ES Kilpatrick, AS Rigby, SL Atkin - Diabetes care, 2008 - Am Diabetes Assoc
OBJECTIVE—Debate remains as to whether short-or long-term glycemic instability confers a
risk of microvascular complications in addition to that predicted by mean glycemia alone. In …

Insulin Resistance, the Metabolic Syndrome, and Complication Risk in Type 1 Diabetes: “Double diabetes” in the Diabetes Control and Complications Trial

ES Kilpatrick, AS Rigby, SL Atkin - Diabetes care, 2007 - Am Diabetes Assoc
OBJECTIVE—The presence of insulin resistance and the metabolic syndrome are known
risk markers for macrovascular disease in patients with and without type 2 diabetes. This …

Beneficial effects of soy phytoestrogen intake in postmenopausal women with type 2 diabetes

V Jayagopal, P Albertazzi, ES Kilpatrick… - Diabetes …, 2002 - Am Diabetes Assoc
OBJECTIVE—Phytoestrogen consumption has been shown to reduce risk factors for
cardiovascular disease. Type 2 diabetes confers an adverse cardiovascular risk profile …

The efficacy and safety of insulin degludec given in variable once-daily dosing intervals compared with insulin glargine and insulin degludec dosed at the same time …

L Meneghini, SL Atkin, SCL Gough, I Raz… - Diabetes …, 2013 - Am Diabetes Assoc
OBJECTIVE The requirement to inject current basal insulin analogs at a fixed time each day
may complicate adherence and compromise glycemic control. This trial evaluated the …

The effect of glucose variability on the risk of microvascular complications in type 1 diabetes

ES Kilpatrick, AS Rigby, SL Atkin - Diabetes care, 2006 - Am Diabetes Assoc
OBJECTIVE—It is not known whether glycemic instability may confer a risk of microvascular
complications that is in addition to that predicted by the mean blood glucose (MBG) value …

Increased expression of estrogen receptor β mRNA in tamoxifen-resistant breast cancer patients

V Speirs, C Malone, DS Walton, MJ Kerin, SL Atkin - Cancer research, 1999 - AACR
Tamoxifen is currently the first-line therapy for treatment of hormone-dependent breast
cancer. However, despite initial benefits, most patients eventually relapse. Two groups of …

Efficacy and safety of liraglutide versus placebo as add-on to glucose-lowering therapy in patients with type 2 diabetes and moderate renal impairment (LIRA-RENAL) …

MJ Davies, SC Bain, SL Atkin, P Rossing… - Diabetes …, 2016 - Am Diabetes Assoc
OBJECTIVE Renal impairment in type 2 diabetes limits available glucose-lowering treatment
options. This trial was conducted to establish the efficacy and safety of liraglutide as an add …