Background It is widely believed that females have longer telomeres than males, although
results from studies have been contradictory. Methods We carried out a systematic review …

Background Although gastric bypass surgery accounts for 80% of bariatric surgery in the
United States, only limited long-term data are available on mortality among patients who …

Blood pressure is a heritable trait influenced by several biological pathways and responsive
to environmental stimuli. Over one billion people worldwide have hypertension (≥ 140 mm …

Essential hypertension is a common human disease believed to reautt from the interplay of
multiple genetic and environmental determinants. In genetic studies of two large panels of …

Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic
outcomes, independent of overall adiposity. To increase our understanding of the genetic …

Context Extreme obesity is associated with health and cardiovascular disease risks.
Although gastric bypass surgery induces rapid weight loss and ameliorates many of these …

Background Few long-term or controlled studies of bariatric surgery have been conducted to
date. We report the 12-year follow-up results of an observational, prospective study of Roux …

Heterozygous familial hyperchotesterolemia (FH) is a serious disorder causing twice normal
lowdensity lipoprotein cholesterol levels early in childhood and very early coronary disease …

The question of whether or not nonsurgical intentional or voluntary weight loss results in
reduced mortality has been equivocal, with long-term mortality following weight loss being …

Mildly increased serum bilirubin has recently been suggested as a protective factor, possibly
reducing the risk of coronary artery disease (CAD) by acting as an antioxidant. We tested …