User profiles for "author:Tadashi Toyama"

Tadashi Toyama

- Verified email at staff.kanazawa-u.ac.jp - Cited by 4177

Tadashi Toyama

- Verified email at yamanashi.ac.jp - Cited by 1941

Effects of sodium-glucose cotransporter-2 inhibitors on cardiovascular events, death, and major safety outcomes in adults with type 2 diabetes: a systematic review …

JHY Wu, C Foote, J Blomster, T Toyama… - The lancet Diabetes & …, 2016 - thelancet.com
Background In patients with type 2 diabetes, sodium-glucose cotransporter-2 (SGLT2)
inhibitors are known to reduce glucose concentrations, blood pressure, and weight, but to …

Trajectories of kidney function in diabetes: a clinicopathological update

M Oshima, M Shimizu, M Yamanouchi… - Nature Reviews …, 2021 - nature.com
Diabetic nephropathy has been traditionally diagnosed based on persistently high
albuminuria and a subsequent decline in glomerular filtration rate (GFR), which is widely …

Prevalence of chronic kidney disease in Asia: a systematic review and analysis

T Liyanage, T Toyama, C Hockham, T Ninomiya… - BMJ global …, 2022 - gh.bmj.com
Introduction The burden of chronic kidney disease (CKD) is growing rapidly around the
world. However, there is limited information on the overall regional prevalence of CKD, as …

Sodium-glucose cotransporter 2 inhibitors and risk of hyperkalemia in people with type 2 diabetes: a meta-analysis of individual participant data from randomized …

BL Neuen, M Oshima, R Agarwal, C Arnott… - Circulation, 2022 - Am Heart Assoc
Background: Hyperkalemia increases risk of cardiac arrhythmias and death and limits the
use of renin-angiotensin-aldosterone system inhibitors and mineralocorticoid receptor …

Effect of SGLT2 inhibitors on cardiovascular, renal and safety outcomes in patients with type 2 diabetes mellitus and chronic kidney disease: a systematic review and …

T Toyama, BL Neuen, M Jun, T Ohkuma… - Diabetes, Obesity …, 2019 - Wiley Online Library
Aim The use of sodium glucose co‐transporter 2 (SGLT2) inhibitors in patients with type 2
diabetes mellitus (T2DM) and chronic kidney disease (CKD) has been limited, primarily …

Accelerated biodegradation of pyrene and benzo [a] pyrene in the Phragmites australis rhizosphere by bacteria–root exudate interactions

T Toyama, T Furukawa, N Maeda, D Inoue, K Sei… - Water research, 2011 - Elsevier
We investigated the biodegradation of pyrene and benzo [a] pyrene in Phragmites australis
rhizosphere sediment. We collected P. australis plants, rhizosphere sediments, and …

Long-term outcomes of Japanese type 2 diabetic patients with biopsy-proven diabetic nephropathy

M Shimizu, K Furuichi, T Toyama, S Kitajima… - Diabetes …, 2013 - Am Diabetes Assoc
OBJECTIVE We evaluated the structural-functional relationships and the prognostic factors
for renal events, cardiovascular events, and all-cause mortality in type 2 diabetic patients …

[HTML][HTML] Expression and localization of tissue kallikrein mRNAs in human epidermis and appendages

N Komatsu, M Takata, N Otsuki, T Toyama… - Journal of investigative …, 2003 - Elsevier
Tissue kallikreins are a group of serine proteases that are found in many organs and
biologic fluids. Tissue kallikrein genes (KLKs) are found on chromosome 19q13. 3–4 as a …

Benefits and harms of oral anticoagulant therapy in chronic kidney disease: a systematic review and meta-analysis

JT Ha, BL Neuen, LP Cheng, M Jun… - Annals of internal …, 2019 - acpjournals.org
Background: Effects of oral anticoagulation in chronic kidney disease (CKD) are uncertain.
Purpose: To evaluate the benefits and harms of vitamin K antagonists (VKAs) and non …

Clinical impact of albuminuria and glomerular filtration rate on renal and cardiovascular events, and all-cause mortality in Japanese patients with type 2 diabetes

T Wada, M Haneda, K Furuichi, T Babazono… - Clinical and …, 2014 - Springer
Background The number of patients suffering from diabetic nephropathy resulting in end-
stage kidney disease is increasing worldwide. In clinical settings, there are limited data …