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Topic Collection

Advancing Care and Outcomes for Patients with Diabetic Kidney Disease

Submission Deadline: 7th February 2024 We are pleased to offer a 25% discount on the Article Processing Charge (APC) for articles submitted to this Topic Collection. Please visit our author hub for more information about the benefits of submitting to a Topic Selection. Chronic kidney disease (CKD) represents a particularly challenging complication of diabetes, occurring in approximately 30-40% of patients with diabetes. The presence of CKD complicates overall diabetes management and is associated with increased risks for poor kidney, heart, and mortality outcomes. Fortunately for patients with diabetic kidney disease (DKD), recent therapeutic advancements offer treatments capable of addressing residual risk as an add-on to standard-of-care renin-angiotensin system (RAS) blockade to slow kidney disease progression and reduce cardiovascular and mortality risk. Recent approvals of agents from the sodium-glucose cotransporter-2 (SGLT2) inhibitor and nonsteroidal mineralocorticoid receptor antagonist classes to improve outcomes in patients with DKD has fuelled research efforts to better understand the pathophysiology of cardiorenal syndrome and how these and future therapies in development mitigate kidney, heart, and mortality risks. Furthermore, current evidence shows that many of the patients who could derive the most benefit from novel organ protective therapies are the least likely to receive them, thus necessitating the development of new care models to optimise use of guideline directed therapies in patients with DKD. For this Topic Collection, we are seeking original research articles and timely review articles focusing on scientific and clinical advancements informing the treatment and care of patients with DKD. Potential topics of interest include, but are not limited to, articles focusing on:
  • Mechanisms of cardiorenal benefit with established and/or experimental therapies
  • Insights into the pathophysiology of cardiorenal syndrome
  • Standard of care utilisation of therapies for kidney and heart protection
  • Novel models of care delivery for patients with DKD
Please see the instructions for authors for submission requirements for each article type. To submit your article, please follow these instructions and select ‘Advancing Care and Outcomes for Patients with Diabetic Kidney Disease’ as the Topic Collection. All submitted articles will be subject to the journal's normal peer review process. Articles accepted for publication will be published upon acceptance. Visit our author hub for more information regarding the publication process for topic collections. Key words: Cardiorenal, Chronic kidney disease, Diabetes, Diabetic kidney disease, End-stage kidney disease, Finerenone, GLP-1 receptor agonists, Guideline directed medical therapy, Kidney outcomes, SGLT2 inhibitors, Team-based care

Guest Editors

Joshua J. Neumiller College of Pharmacy and Pharmaceutical Sciences Washington State University https://orcid.org/0000-0002-4734-7402