You are here

  • Home
  • Archive
  • Volume 4, Issue 1
  • Indirect measure of visceral adiposity ‘A Body Shape Index’ (ABSI) is associated with arterial stiffness in patients with type 2 diabetes

Article Text

Article menu

Download PDFPDF

XML
Cardiovascular and metabolic risk
Indirect measure of visceral adiposity ‘A Body Shape Index’ (ABSI) is associated with arterial stiffness in patients with type 2 diabetes
  1. Ryotaro Bouchi1,
  2. Masahiro Asakawa1,
  3. Norihiko Ohara1,
  4. Yujiro Nakano1,
  5. Takato Takeuchi1,
  6. Masanori Murakami1,
  7. Yuriko Sasahara1,
  8. Mitsuyuki Numasawa1,
  9. Isao Minami1,
  10. Hajime Izumiyama1,2,
  11. Koshi Hashimoto1,3,
  12. Takanobu Yoshimoto1,
  13. Yoshihiro Ogawa1,4
  1. 1Department of Molecular Endocrinology and Metabolism, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan
  2. 2Center for Medical Welfare and Liaison Services, Tokyo Medical and Dental University, Tokyo, Japan
  3. 3Department of Preemptive Medicine and Metabolism, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan
  4. 4Department of CREST, Japan Agency for Medical Research and Development, Tokyo, Japan
  1. Correspondence to Dr Ryotaro Bouchi; bouchi.mem{at}tmd.ac.jp

Abstract

Objective Among indirect measures of visceral adiposity, A Body Shape Index (ABSI), which is defined as waist circumference (WC)/(body mass index (BMI)2/3×height1/2), is unique in that ABSI is positively correlated with visceral adiposity and is supposed to be independent of BMI. ABSI has been also shown to be linearly and positively associated with visceral fat mass and all-cause and cardiovascular disease (CVD) in the general population. It is, however, uncertain whether ABSI could be associated with arterial stiffness in patients with diabetes.

Methods This is a cross-sectional study of 607 patients with type 2 diabetes (mean age 64±12 years; 40.0% female). Visceral fat area (VFA, cm2) and subcutaneous fat area (SFA, cm2) were assessed with a dual-impedance analyzer. In order to estimate the risk for CVD, brachial-ankle pulse wave velocity (baPWV, cm) was used for the assessment of arterial stiffness.

Results ABSI was significantly and positively correlated with VFA (r=0.138, p=0.001) and negatively associated with BMI (r=−0.085, p=0.037). The correlation of z-score for ABSI with VFA remained significant (r=0.170, p<0.001) but not with BMI (r=0.009, p=0.820). ABSI (standardized β 0.095, p=0.043) but not WC (standardized β −0.060, p=0.200) was significantly and positively correlated with baPWV in the multivariate model including BMI as a covariate.

Conclusions ABSI appears to reflect visceral adiposity independently of BMI and to be a substantial marker of arterial stiffening in patients with type 2 diabetes.

  • Visceral Obesity
  • Arterial Stiffness
  • Anthropometry
  • Type 2 Diabetes

This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

https://doi.org/10.1136/bmjdrc-2015-000188

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    View Full Text